Community & Collaboration Builder | Human Data Sharing Expert | Bioinformatics & Metadata Enthusiast | Open Science Advocate | she/her
Currently I am Coordinator for the European Genome-phenome Archive (EGA), a controlled access resource for managing sensitive human data. I am based at EMBL’s European Bioinformatics Institute based in Cambridge, UK. I am responsible for delivery of EGA services and coordinating the EGA roadmap with our collaborators to support our strategic goals. Prior to becoming Coordinator, I was the Project Lead for coordinating archive and distribution of whole genome sequencing data from the UK Biobank resource. I joined EMBL-EBI in 2017 as part of the Human Cell Atlas (HCA) Data Coordination Platform team, where I developed the HCA metadata standard and worked closely with data generators to submit the first single cell sequencing datasets to the HCA.
After completing my BSc degree in Bioinformatics at Saint Vincent College, I earned my PhD in Bioinformatics at the University of Michigan studying post-transcriptional gene regulation in the model organisms C. elegans (nematode) and S. cerevisiae (budding yeast). I studied mechanisms of regulation and expression of small, functional RNAs including microRNAs and germline-specific piRNAs. I also studied protein-RNA interactions and how they contribute to post-transcriptional gene regulation. If interested, you can read more in my public thesis.
I then started a postdoctoral fellowship at Johns Hopkins University, continuing my exploration of protein-RNA interactions through re-analysis of published deep sequencing data. I also piloted experiments directly sequencing full-length messenger RNAs in nematodes using nanopore sequencing to explore the diversity of the nematode transcriptome. During my postdoc, two key things happened that shaped the trajectory of my career. First, I gained an appreciation for the challenges facing researchers who want to re-use published sequencing datasets. Second, I joined the Galaxy Project team to develop and deliver bioinformatics training and realised my passion is supporting “Science as a Service” resources.
Some really cool communities that I am proud to be associated with:
A program for people interested in applying open principles in their work and becoming Open Science ambassadors in their communities
A policy-framing and technical standards-setting organization seeking to enable responsible genomic data sharing within a human rights framework
A collection of open bioinformatics tutorials and training resources developed and maintained by the global Galaxy community
An international group of researchers aiming to create comprehensive reference maps of all human cells — the fundamental units of life — as a basis for understanding human health and diagnosing, monitoring, and treating disease
I love all things Open Science: open data, open and welcoming communities, open software, open workflows, open training materials, open publishing and peer-reviewing, oh my!
I love mentoring individuals to help them achieve their professional and personal goals.